Search on: PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 2 
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Descriptor English:   Protein Tyrosine Phosphatase, Non-Receptor Type 2 
Descriptor Spanish:   Proteína Tirosina Fosfatasa no Receptora Tipo 2 
Descriptor Portuguese:   Proteína Tirosina Fosfatase não Receptora Tipo 2 
Tree Number:   D08.811.277.352.650.775.300.200
D12.644.360.585.200
D12.776.476.564.200
Definition English:   A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely. 
History Note English:   2008(1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52697 
Unique Identifier:   D054578 

Occurrence in VHL:
 

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